- Anne Atkinson Chamberlayne Collection., 1742/19632
- Bugg Family Collection., 1876/19574
- Business Office Accounting Ledgers, 1884/19233
- Commencement Programs Collection, 1863/20212
- Dabney Lancaster and Lancaster Family Records, 1848/19743
- Dr. Wayne McWee Historical Newspapers, 1863/19622
- Elizabeth Burger Jackson Collection, 1950/20061
- Faculty Meeting Minutes, 1884/19642
- George William Jeffers Collection, 1910/19861
- Harwood Family Collection, 1806/19832
- James Elliott Walmsley Collection, 1810/19392
- Kate Childress Autograph Book, 1884/18892
- Katherine Courtenay Johnston Collection, 1829/19461
- Mattoon Family Collection, 1870/19661
- Paulett Family Business Records, 1877/19293