- E. E. Meredith, Collector, Broadsides and Other Material regarding Jackson and Marion Counties, 1855/19511
- E. L. Mathers and Max Mathers, Compilers, Monongalia County Scrapbook, 1838/19511
- E.J. Van Liere, Collector, Medical Journal Prospectus and Physicians Rate Sheet, 1865/19011
- Earhart Family Papers, 1788/192812
- Earl Gregg Swem Family Papers, 1871/19844
- Earl Gregg Swem Genealogy Collection, 1719/19827
- Earl Gregg Swem Papers, 1927/19651
- Earl L. Core (1902-1984) Papers, 1756/198516
- Earl L. Core, Collector, Papers, 1840/19271
- Earl and Jewell Ratliff Collection, 1860/2013, bulk 1920/19902
- Early Orndorff Papers, 1868/19421
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/1875214
- Eastern State Hospital Records, 1862/1957, bulk 1862/18682
- Easton-Avery Community History, 1769/19271
- Ebenezer Church of Barbour County, Membership Records, 1836/19211