- Francis Harrison Pierpont (1814-1899) Papers, 1811/1949, bulk 1860/189930
- McGavock Family Papers, 1760/188830
- Duke Family Papers
1764-198329
- James Washington Singleton Papers, 1770/1975, bulk 1850/192029
- McCauley family papers, 1790/200829
- West Virginia University, President's Office, Records, 1864/198929
- Long/Trail Southeastern West Virginia Historical Records, 1870/202528
- Samuel Price, Lawyer and Politician, Papers, 1788/188828
- Cocke Family Papers, 1725-193927
- Papers of Mark Twain
1862-1946, bulk 1872-191027
- Shenandoah County Historical Society Collection, 1147/200027
- Thomas Browse Family Papers, 1785/1942, bulk 1830/191027
- Virginia Cities Collection, 1663/198027
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/199727
- Robert Waldsmith Collection of stereographs and cabinet cards, 1856/198126