- "Home School for Young Boys" Broadside, 18701
- A. Gold and Company ledgers, 1866/18803
- Abraham Lincoln Collection, 1860/19651
- Ackerly Family Papers6
- Administration records collection, 1776/197648
- African and African American photograph collection, 1850/19451
- Alamby Miller Scrapbook, 1864/18701
- Alexander Lockhart Nelson papers, 1848/19021
- Alexander Sterrett Paxton Papers, 1858/1959, bulk 1861/18652
- Alexander Tedford "Ted" Barclay correspondence, 1861/18641
- Alexander, Fultz, and Willson Families Collection, 1770/19701
- Alfred Leyburn Papers, 1823/1899, bulk 1830/18391
- Almanac collection, 1850/19092
- Alphin Family Photographs, 1870/19301
- American Civil War collection, 1860/18952