- A. E. Dick Howard papers, 1928/20171
- African American man tintype portrait, 1865/19001
- Albert Frederick Wilson papers, 1840/19343
- Albert R. Gallatin papers, 1795/18281
- Albert Taylor Bledsoe and Sophia Bledsoe Herrick letters, 1858/19081
- Alderman family papers, 1779/19617
- Alexander Family Papers
1800-18906
- Alfred C. Garnett, Jr. Papers
1868-19451
- Alfred Spates Papers
1843-19096
- Alice and Phoebe Cary Collection
1850-18691
- Alice and Phoebe Cary Collection
1858-18901
- Anna Maria Hickman Otis Mead Chalmers family papers, 1821/189724
- Arlene Keeling Collection, 1861/20061
- Armstead L. Robinson papers, 1848/2001, bulk 1967/199211
- Aubrey E. Strode papers, 1861/19694