- Alexandria History Collection (MS240), 1767/20089
- Alexandria Library Company Records (MS002), 1794/20073
- Alexandria Scrapbook Collection (MS003), 1830/18931
- Armistead Boothe Papers (MS164), 1803/199014
- Boush/Asher Family Collection (MS234), 1856/19494
- Cazenove Family Papers (MS212), 1786/19707
- Chapman Family Collection (MS274), 1828/19632
- Charles L. Sampson Collection (MS126), 1841/19863
- Daniel O'Sullivan Collection (MS141), 1850/19124
- Edith Moore Sprouse Papers (MS313), 1960/20031
- Eleanor Lee Templeman Collection (MS061), 1810/19901
- Esther Holliday Green Collection (MS073), 1859/19828
- Ethelyn Cox Collection (MS287), 1956/19801
- Florence Davidson Collection (MS318), 1856/19831
- Helen Norris Cummings Papers (MS072), 1865/19495