- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18654,292
- Siler Family Papers, 1848/19681,145
- Francis Harrison Pierpont (1814-1899) Papers, 1811/1949, bulk 1860/1899462
- Cocke Family Papers, 1725-1939442
- Union Volunteers of West Virginia Regiments, Civil War Service Records, 1861/1865262
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/1875194
- Robert Taylor Preston Papers, 1849/1871, bulk 1861/1862156
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954139
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960138
- Sheet Music Collection, 1827/1974128
- Emory L. Kemp Papers regarding Industrial History, 1735/2021127
- Ohio County (W. Va.) Court Records and Miscellaneous Papers, 1772/1954, bulk 1777/1930109
- Gregory A. Prince Mormon Studies Collection, 1813/2020108
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900107
- Restoration Files for the Historic Structures Report, 1750/2005105