- Siler Family Papers, 1848/19681,143
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/1875927
- Cocke Family Papers,
1725-1939253
- David Hunter Strother, Artist, Artwork and Papers, 1744/1996, bulk 1833/1887157
- Sheet Music Collection, 1827/1974152
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954143
- Carter Family Papers, 1667/1862, bulk 1792/1861129
- Emory L. Kemp Papers regarding Industrial History, 1735/2021125
- Ohio County (W. Va.) Court Records and Miscellaneous Papers, 1772/1954, bulk 1777/1930115
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900110
- Restoration Files for the Historic Structures Report, 1750/2005106
- Gregory A. Prince Mormon Studies Collection, 1813/2020104
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960101
- Galt Papers (III), 1750/199192
- Historic newspapers collection, 1757/195787