- Alexander Hamilton, Jr. Letters, 1832/18331
- Alexander Lockhart Nelson papers, 1848/19021
- Alexander M. Davis Papers, 1850/18924
- Alexander McNutt Glasgow Family Papers, 1823/19036
- Alexander Sterrett Paxton Papers, 1858/1959, bulk 1861/18652
- Alexander Von Humboldt Portrait Print, 1855/18901
- Alexander, Fultz, and Willson Families Collection, 1770/19701
- Alexandria Black Family Reunion Digital Collection, 1937/20051
- Alexandria Gazette Ledgers (MS026), 1833/186611
- Alexandria History Collection (MS240), 1767/200831
- Alexandria Library Company Records (MS002), 1794/200711
- Alexandria Scrapbook Collection (MS003), 1830/18932
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Alfred Hughes Stock Certificates and Receipts, 1852/18651
- Alfred Leyburn Papers, 1823/1899, bulk 1830/18391