- Virginia Counties Collection, 1600/2000, bulk 1730/189049
- University of Virginia School of Nursing, 1819/201622
- Historic newspapers collection, 1757/195721
- Alexandria History Collection (MS240), 1767/200817
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/199510
- North American 19th century theatre broadside collection, 1850/186710
- Atkeson-Morgan Family Papers, 1833/1923, bulk 1850/19009
- David Hunter Strother, Artist, Artwork and Papers, 1744/1996, bulk 1833/18879
- Galt Papers (III), 1750/19919
- James Washington Singleton Papers, 1770/1975, bulk 1850/19209
- Peter family papers, 1722/19329
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/19609
- Francis Harrison Pierpont (1814-1899) Papers, 1811/1949, bulk 1860/18998
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/19748
- Siler Family Papers, 1848/19688