- Alexander Brown Papers (I), 1815/19103
- Allen-Kean-Laurence family letters, 1837/19601
- Armistead-Cocke Papers, 1680/19173
- Austin-Twyman Papers, 1765/193913
- Barnes Family Papers, 1797/1926, bulk 1818/18751
- Baytop-Fitzhugh Papers, 1840/18662
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/189213
- Bound Music Collection, 1800/197025
- Bozarth Family Papers, 1931/1985, bulk 1931/19621
- Brown, Coalter, Tucker Papers (II), 1791/19203
- Brown, Coalter, Tucker Papers (III), 1838/19641
- Bruton Parish Church (Williamsburg, Va.) records, 1662/2010, bulk 1900/20001
- Byers Family Papers, 1806/19294
- C. W. Murdaugh Papers, 1853/18781
- Cabell Family Papers, 1693/1913, bulk 1743/18232