- Siler Family Papers, 1848/19681,145
- Cocke Family Papers, 1725-1939491
- Southall Papers, 1807/1904335
- Tucker-Coleman papers, 1664/1945, bulk 1770/1907185
- Carter Family Papers, 1667/1862, bulk 1792/1861181
- Sheet Music Collection, 1827/1974128
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954122
- Emory L. Kemp Papers regarding Industrial History, 1735/2021112
- Ohio County (W. Va.) Court Records and Miscellaneous Papers, 1772/1954, bulk 1777/1930112
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900110
- Austin-Twyman Papers, 1765/1939104
- Restoration Files for the Historic Structures Report, 1750/2005104
- Galt Papers (I), 1745/189295
- Virginia Counties Collection, 1600/2000, bulk 1730/189089
- Monroe County (W. Va.) Court Records and Miscellaneous Papers, 1751/192783