- John Augustine Washington III and family papers, 1789/19949
- Land Records of the MVLA, 1858/20061
- Lawrence Lewis family papers, 1785/18581
- Lawrence Washington collection of Washington family papers, 1787/19321
- Lily Laughton Papers, 1850/18914
- Maps of Mount Vernon and the surrounding areas, 1857/19921
- Martha Washington collection, 1761/18021
- Morley Jeffers Williams Collection, 1602/19678
- Papers of Christine Meadows, Curator, 1960/19971
- Papers of the Mount Vernon Ladies' Association, 1858/20162
- Papers of the Superintendent and Resident Director, 1850/19965
- Peter family papers, 1722/193274
- Restoration Files for the Historic Structures Report, 1750/2005104
- Taylor collection of Lewis family papers, 1700/19501
- Washington forgeries, facsimiles, and bookplates collection, 1863/19992