- History Harvest collection of digitized images of religious materials, 1880/20121
- Hoak Ledger, 1794/18552
- Hooke family letters, 1845/18492
- James Madison Memorabilia, 1796/19512
- John A. Sawhill Collection, 1756/18481
- John G. Stewart Papers, 1761/2002, bulk 1953/19735
- John H. Grabill Papers, 1843/1981, bulk 1894/19224
- John L. Heatwole Collection of Shenandoah Valley History, 1802/19013
- John T. Harris papers, 1771/1937, bulk 1850/190018
- John W. Wilson Collection, 1766/19635
- Liskey Collection of Heavner Family Papers, 1788/19675
- Manley Family papers, 1707/19539
- Margaret B. Burruss Collection of Scott and Saufley Family Papers, 1786/19123
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19108
- Marianne L. Garber Collection of Shenandoah Valley Documents, 1780/18995