- S. Maria Elliott Family Collection, 1826/19421
- S. Robbins and E. N. Gates records of accounts, 1839/18422
- Sabra Lucinda (Miner) Sturgiss Papers, 1838/19091
- Saint Andrew's Society collection, 1861/19952
- Salt Sulphur Springs Records, 1819/19321
- Salt Sulphur Springs Records, 1825/18831
- Samuel B. Finley Account Books, 1802/18594
- Samuel D. Morton and Co. Account Books, 1826/18914
- Samuel Davidson Family Papers, 1823/19394
- Samuel E. Smith record book, 1818/18502
- Samuel F. Bright account books, 1826/18611
- Samuel G. Clark Liberty Iron Furnace Collection, 1809/19172
- Samuel H. Yonge papers, 1890/19351
- Samuel Henley Letter to Mr. Johnson, 1775/18001
- Samuel Jacob Financial Papers, 1824/1921, bulk 1824/18991