- Anna Maria Hickman Otis Mead Chalmers family papers, 1821/18972
- Burnley Family papers, 1808/19641
- Carter Glass Papers, 1820/19461
- Celestia "Essie" Wade Butler Smith papers, 1793/20021
- Fernande Gontier papers, 1787/20052
- Goss family papers, 1820/2014, bulk 1820/19303
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18652
- John Taylor of Caroline papers, 1777/17941
- Laine family papers, 1772/19612
- Morton-Halsey family papers, 1833/19511
- Ogden family papers, 1801/19792
- Ollen Lawrence Burnette, Jr. papers, 1815/20141
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/19743
- The University of Virginia Jefferson Papers, 1751/18982
- University of Virginia School of Nursing, 1819/201622