- Ann Smith Academy Papers, 1807/19101
- Anna Burton Ellett Collection, 1751/19322
- Anna Maria Hickman Otis Mead Chalmers family papers, 1821/189710
- Anne Atkinson Chamberlayne Collection., 1742/19631
- Anne Hulme Diary, 1838/18502
- Anthony Ware, Miscellaneous Papers, 1773/18861
- Appalachian Prints Collection, 1839/2010, bulk 1859/19093
- Appomattox Manor Music Collection, 1800/1940, bulk 1850/19101
- Archibald Stuart Ledgers, 1757/18521
- Archibald Woods Papers, 1777/1846, bulk 1783/184617
- Aretas Brooks Fleming (1839-1923) Papers, 1784/19241
- Aretas Brooks Fleming Papers, 1784/19241
- Armistead Boothe Papers (MS164), 1803/19908
- Armistead Papers, 1736/18971
- Armistead-Cocke Papers, 1680/19175