- James Washington Singleton Papers, 1770/1975, bulk 1850/192025
- Webb Family Papers, 1790/197524
- Hodges Family Papers, 1754/197915
- Robert Morton Hughes Papers, 1754/195013
- Elie Beatty Papers, 1814/18478
- Eloise Word Skewis Papers, 1777/19077
- Mason C. Andrews Papers, 1777/2010, bulk 1950/19906
- Finlay Forbes Ferguson Papers, 1812/19755
- Richard A. Rutyna Papers, 1763/20115
- Allen-Johnson Family Papers, 1838/19473
- Benjamin A. Banks Papers, 1855/19743
- Rose-Tunstall Family Papers, 1809/19473
- Admiral John Randolph Tucker Papers, 1865/18972
- Harold S. Wilson Papers, 1813/19782
- Nineteenth Century Stethoscope, 1800/18602