- United States Federal Nineteenth Century Government Publications, 1826/18784
- United States Military Collection, 1776/19463
- University Archives Artifact Collection, 1693/2014, bulk 1900/20113
- University Archives Bound Volumes Collection, 1693/19935
- University Archives Diploma Collection, 1756/19842
- University of Virginia Claude Moore Health Sciences Library Art and Artwork collection, 1819/20161
- University of Virginia Medical Illustrations collection, 1760/1969, bulk 03
- University of Virginia School of Medicine records, 1825/20205
- University of Virginia School of Nursing, 1819/201623
- Unknown Woman's Writing Exercise Book, 18321
- Upshur Family Papers, 1662/19366