- Henry Ruffner collection, 1815/18675
- Hiram Martz Papers, 1830/18731
- Isaac Bird correspondence, 1824/18341
- Jacob Fuller scrapbook, 1774/18783
- James D. Davidson Scrapbooks, 1832/18782
- James Lewis Howe Papers, 1893/19511
- James River and Kanawha Company Papers - John Jordan, 18301
- John C. Calhoun correspondence, 1818/18342
- Joseph H. Hennage Scripophily Collection, 1800/19501
- Land Grants, 1749/19852
- Land Surveys, 1815/19431
- Lee-Jackson Foundation collection, 1775/19133
- Legal Documents, 1742/18953
- Lexington Presbyterian Church collection, 1824/1927, bulk 1877/19271
- Lexington Presbyterian Church records (CURRENTLY UNPUBLISHED)1