- Abner Johnson Leavenworth Papers, 1825/186110
- Austin-Twyman Papers, 1765/19395
- B. J. Spruell Account Book, 1782/18361
- Barry S. Martin collection of historical manuscripts and documents, 1771/18301
- Barton Myers Papers, 1878/19251
- Benjamin Stoddert Ewell Papers, 1784/1934, bulk 1830/18924
- Blair, Banister, Braxton, Horner, Whiting Papers, 1760/1890, bulk 1765/18173
- Booton-Modesitt Family Papers, 1809/1880, bulk 1820/18502
- Borland Family Papers, 1771/19401
- Bound Music Collection, 1800/19707
- Brown, Coalter, Tucker Papers (I), 1790/19291
- Brown, Coalter, Tucker Papers (II), 1791/19202
- Bruton Parish Church (Williamsburg, Va.) records, 1662/2010, bulk 1900/20001
- Buckingham County, Va. Merchant's Journal, 1830/18311
- Byers Family Papers, 1806/19291