- Aaron Harmon Collection (MS249), 1815/18361
- Alexandria History Collection (MS240), 1767/20081
- Alexandria Library Company Records (MS002), 1794/20071
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Armistead Boothe Papers (MS164), 1803/19901
- Cazenove Family Papers (MS212), 1786/19701
- Eleanor Lee Templeman Collection (MS061), 1810/19901
- John Thomas Ricketts Papers (MS071), 1787/19041
- Kennedy-Barton Book Collection (MS277), 1753/18341
- Lyceum Construction Records (MS245), 1790/18591
- Mary Louisa Slacum Benham Papers (MS062), 1802/18841
- McKnight, Piercy, and Jacobs Collection (MS051), 1792/19731
- Milton Penn Collection (MS267), 1794/18931
- Periclean Society Records (MS006), 1821/18241
- Phillip Fendall Papers (MS190), 1817/18571