- John Augustine Washington III and family papers, 1789/19941
- John G. Stewart Papers, 1761/2002, bulk 1953/19731
- John Janney Papers,, 1811/1994, bulk 1840/18801
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18651
- John Marshall Papers, 1755/18353
- John Taylor of Caroline papers, 1777/17941
- John Tyler, Jr. Papers, 1800/19281
- John W. Warner papers, 1967/2009, bulk 1967/20081
- Manuscripts - Geographic Names, Business Names and Subjects, 1725/19494
- Margaret B. Ballard, Compiler, Monroe County Historical Papers and Other Material, 1783/2021, bulk 1910/19702
- Mason C. Andrews Papers, 1777/2010, bulk 1950/19901
- Moreland Family Papers, 1788/19441
- Paul G. Caplan Papers, 1890/20041
- Peter family papers, 1722/19321
- Philip Lightfoot Papers, 1778/18006