- Burnley Family papers, 1808/19641
- Bushrod Washington family papers, 1662/18354
- Byers Family Papers, 1806/19291
- C-SPAN records, 1809/2012, bulk 1978/20122
- Cabaniss Family Papers, 1800/18372
- Cabell Family Papers, 1693/1913, bulk 1743/18232
- Calvert Walke Tazewell Papers, 1900/19971
- Capt. William Sommerville (1756-1826) Papers, 1799/18881
- Carl R. Dolmetsch Papers, 1751/19901
- Carol R. Lubin papers, 1960/19812
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Cazenove Family Papers (MS212), 1786/19704
- Celestia "Essie" Wade Butler Smith papers, 1793/20021
- Chapin collection of Washington & Custis family documents, 1758/18291
- Chappelear Collection, 1788/19591