- Anderson Family papers, 1755/19589
- Andrew Lindamood papers, 1768/18171
- Andrew Reid Account Book, 1787/18371
- Andrew Reid record book photocopy, 1803/18281
- Anna Burton Ellett Collection, 1751/19321
- Archibald Stuart Ledgers, 1757/18521
- Archibald Stuart Papers, 1790/18161
- Archibald Woods Papers, 1777/1846, bulk 1783/184683
- Armistead Boothe Papers (MS164), 1803/19901
- Armstead L. Robinson papers, 1848/2001, bulk 1967/19921
- Augusta County and Bath County, Virginia, Receipts, 1780/18481
- Austin-Twyman Papers, 1765/193921
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Baker Family Papers, 1805/19111
- Bank of Rockbridge Currency and Lexington Lottery Ticket collection, 1803/18621