- Austin-Twyman Papers, 1765/193925
- Blow Family Papers, 1613/1960, bulk 1770/18752
- Borland Family Papers, 1771/19403
- Brown, Coalter, Tucker Papers (I), 1790/19298
- Brown, Coalter, Tucker Papers (II), 1791/19202
- Carter Family Papers, 1667/1862, bulk 1792/186110
- Corie Lynn Dorset Rivers Collection of Ludwell-Lee-Slater Family Papers, 1805/19231
- Dangerfield Lewis papers, 1799/18542
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/19002
- Hart collection, 1762/19391
- Henkel Family Papers, 1783/18741
- Jerdone Family papers, 1753/18905
- John Marshall Papers, 1755/18353
- John Tyler, Jr. Papers, 1800/19281
- Manuscripts - Geographic Names, Business Names and Subjects, 1725/19494