- John W. Warner papers, 1967/2009, bulk 1967/20081
- Lexington Arsenal and Virginia Militia records, 1702/18391
- Manuscripts - Geographic Names, Business Names and Subjects, 1725/19493
- Margaret B. Ballard, Compiler, Monroe County Historical Papers and Other Material, 1783/2021, bulk 1910/19702
- Mason C. Andrews Papers, 1777/2010, bulk 1950/19901
- Moreland Family Papers, 1788/19441
- Paul G. Caplan Papers, 1890/20041
- Peter family papers, 1722/19321
- Philip Lightfoot Papers, 1778/18007
- Richard Billups Papers, 1705/1857, bulk 1774/18221
- Richard Wright collection, 1806/20172
- Robert Morton Hughes Papers, 1754/19503
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/19601
- Roy Bird Cook (1886-1961), Collector, Papers, 1774/19431
- Skipwith Family papers, 1760/19771