- Alexander, Fultz, and Willson Families Collection, 1770/19701
- Alexandria History Collection (MS240), 1767/20081
- Alexandria Library Company Records (MS002), 1794/20071
- Alexandria, Virginia City Records (MS019), 1750/1983, bulk 1825/18751
- Allen Family Papers, 1766/19331
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20111
- Anderson Family papers, 1755/19581
- Andrew Delmar Hopkins Papers, 1787/19431
- Andrew Lindamood papers, 1768/18171
- Andrew Reid Account Book, 1787/18371
- Anita Cutright Burnett, Collector, Papers, 1790/19351
- Anna Burton Ellett Collection, 1751/19321
- Anne Atkinson Chamberlayne Collection., 1742/19631
- Anthony Ware, Miscellaneous Papers, 1773/18861
- Appomattox Manor Music Collection, 1800/1940, bulk 1850/19101