- Tyler Family Papers, Group D, 1939/195119
- West Virginia Land Grants Records, 1748/191219
- Virgil Anson Lewis Family History, Research Papers, 1750/200018
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/199718
- Austin-Twyman Papers, 1765/193917
- Richard Billups Papers, 1705/1857, bulk 1774/182215
- Stuart Family Papers, 1785/188015
- Wilkin Family Papers, 1757/1922, bulk 1780/187015
- Emory L. Kemp Papers regarding Industrial History, 1735/202114
- Galt Papers (III), 1750/199114
- Hill Family Genealogy, 1700/1999, bulk 1980/199914
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/199514
- Michael La Vean French documents collection, 1751/185114
- Virginia Cities Collection, 1663/198014
- Campbell Family Papers, 1726/192013