- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20111
- Austin-Twyman Papers, 1765/19397
- Blow Family Papers, 1613/1960, bulk 1770/18752
- Borland Family Papers, 1771/19403
- Brown, Coalter, Tucker Papers (I), 1790/19296
- Bushrod Washington family papers, 1662/18355
- Carter Family Papers, 1667/1862, bulk 1792/186111
- Cazenove Family Papers (MS212), 1786/19701
- Dickson Family Papers, 1769/19245
- Earl L. Core (1902-1984) Papers, 1756/19851
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/19002
- Eloise Word Skewis Papers, 1777/19071
- Emory L. Kemp Papers regarding Industrial History, 1735/20212
- George Washington collection, 1654/17991
- Henkel Family Papers, 1783/18741