- Aurora, Preston County Papers, 1754/19001
- Austin-Twyman Papers, 1765/193915
- Baer Family Papers, 1744/19291
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bakers' Guild Bylaws and Register (Harburg, Germany), 1668/18091
- Barraud Family Papers, 1799/1904, bulk 1810/18601
- Barron Family Papers, 1793/19421
- Barry S. Martin collection of historical manuscripts and documents, 1771/18304
- Baylor Family Papers
1653-19157
- Bell, Kent, Cloyd, Withrow Family Collection, 1780/19983
- Benjamin Layman Papers, 1752/18152
- Benjamin Owen Tyler calligraphic manuscript and Fenno family papers, 1770/18161
- Berkeley Family Papers
1536-present1
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Bigler-Sessler-John Family Papers, 1752/19251