- 17th and 18th century British periodicals, 1600/18001
- A. E. Dick Howard papers, 1928/20171
- Administration records collection, 1776/19761
- Advisory Committee Research Collection, 1772/20174
- Alexander Balmaine Memorandum Book, 1775/18201
- Alexander Haight family collection, 1764/19761
- Alexander Haight family collection, 1764/19771
- Ancella Bickley, Historian, Research Papers regarding African-Americans, 1775/2018, bulk 1970/20111
- Anderson Family papers, 1755/19581
- Andrew Lindamood papers, 1768/18171
- Anna Burton Ellett Collection, 1751/19322
- Austin-Twyman Papers, 1765/19395
- Barry S. Martin collection of historical manuscripts and documents, 1771/18301
- Benjamin Layman Papers, 1752/18151
- Bishop James Madison's preparatory notes on Smith's Wealth of Nations, 1776/18121