- Carl R. Dolmetsch Papers, 1751/19901
- Carpenter Papers, 1765/19221
- Carter Family Papers, 1667/1862, bulk 1792/18611
- Catesby Jones Account Book, 1767/18451
- Chapin collection of Washington & Custis family documents, 1758/18291
- Charles A. Miller Family Papers, 1708/19261
- Charles Campbell Papers, 1743/18961
- Charles Carroll papers, 1770/18261
- Charles H. Bell Papers, 1772/1929, bulk 1852/18751
- Charles Shetler, Curator and Historian, Papers, 1700/19651
- Charles and Joseph Read commonplace book, 1765/17941
- Charles and Thomas Frankland record books, 1740/18111
- Chester McNerney Collection, 1290/19501
- Christian S. Hutter miscellany, 1602/19451
- Christopher A. Dorrance collection, 1750/20001