- Campbell Family Papers, 1726/19206
- Caperton family genealogical research files, 1938/19802
- Carl R. Dolmetsch Papers, 1751/19902
- Carol R. Lubin papers, 1960/19812
- Carpenter Papers, 1765/19221
- Carter Family Papers, 1667/1862, bulk 1792/186123
- Catesby Jones Account Book, 1767/18452
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Chapin collection of Washington & Custis family documents, 1758/18293
- Charles A. Miller Family Papers, 1708/19261
- Charles Brown Papers, 1792/18881
- Charles Campbell Papers, 1743/189612
- Charles Carroll papers, 1770/18261
- Charles H. Bell Papers, 1772/1929, bulk 1852/18752
- Charles Shetler, Curator and Historian, Papers, 1700/19651