- Armistead Papers, 1736/18971
- Armistead-Cocke Papers, 1680/19171
- Ashcraft Family Genealogy, 1732/19721
- Association for the Preservation of Virginia Antiquities, Montgomery County Branch Papers, 1754/1996, bulk 1958/19831
- Aurora, Preston County Papers, 1754/19001
- Austin-Twyman Papers, 1765/19391
- Baer Family Papers, 1744/19291
- Baird Family Papers, 1656/1922, bulk 1656/18481
- Bakers' Guild Bylaws and Register (Harburg, Germany), 1668/18091
- Barry S. Martin collection of historical manuscripts and documents, 1771/18301
- Benjamin Kissam papers, 1755/17761
- Benjamin Layman Papers, 1752/18151
- Benjamin Owen Tyler calligraphic manuscript and Fenno family papers, 1770/18161
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Bigler-Sessler-John Family Papers, 1752/19251