- Cabell Family Papers, 1693/1913, bulk 1743/18232
- Campbell Family Papers, 1726/19201
- Caperton family genealogical research files, 1938/19802
- Carter Family Papers, 1667/1862, bulk 1792/18612
- Catesby Jones Account Book, 1767/18451
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Charles Campbell Papers, 1743/18962
- Christian S. Hutter miscellany, 1602/194514
- Clara L. Lawrence Papers, 1763/19391
- Colvin Papers, 1734/18391
- Commission of Francis Lightfoot Lee et al. as Justices of the Peace from His Majesty's Lt. Governor, Francis Fauqier, 17671
- Dunmore Family Papers (I) [in part photocopies], 1650/18991
- Earl Gregg Swem Genealogy Collection, 1719/19823
- Earl L. Core (1902-1984) Papers, 1756/19851
- Edgar E. MacDonald papers, 1933/19931