- Arthur Lee Philanthropos Address to Virginia General Assembly, 17671
- Austin-Twyman Papers, 1765/19392
- Benjamin Layman Papers, 1752/18151
- Blair, Banister, Braxton, Horner, Whiting Papers, 1760/1890, bulk 1765/18171
- Blow Family Papers, 1613/1960, bulk 1770/18755
- Board of Visitors records, 1757/20233
- Bray Papers, 1730/18173
- C. L. Worthington Papers, 1752/19382
- Cabell Family Papers, 1693/1913, bulk 1743/18232
- Campbell Family Papers, 1726/19201
- Carter Family Papers, 1667/1862, bulk 1792/18612
- Catesby Jones Account Book, 1767/18451
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Charles Campbell Papers, 1743/18962
- Clara L. Lawrence Papers, 1763/19391