- 17th and 18th century British periodicals, 1600/18001
- Alexander Brown Papers (II), 1748/19002
- Armistead Papers, 1736/18971
- Armistead-Cocke Papers, 1680/19172
- Austin-Twyman Papers, 1765/19392
- Baird Family Papers, 1656/1922, bulk 1656/18482
- Bakers' Guild Bylaws and Register (Harburg, Germany), 1668/18091
- Barry S. Martin collection of historical manuscripts and documents, 1771/18301
- Benjamin Layman Papers, 1752/18152
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Blair Family Papers, 1741/17921
- Blow Family Papers, 1613/1960, bulk 1770/18756
- Board of Visitors records, 1757/20232
- Borland Family Papers, 1771/19402
- Brafferton Estate Collection, 1691/19351