- Bray Papers, 1730/18173
- Bruton Parish Church (Williamsburg, Va.) records, 1662/2010, bulk 1900/20005
- C. L. Worthington Papers, 1752/19383
- Cabell Family Papers, 1693/1913, bulk 1743/18239
- Campbell Family Papers, 1726/19203
- Carl R. Dolmetsch Papers, 1751/19901
- Carter Family Papers, 1667/1862, bulk 1792/186118
- Cathrine Cheshire Land Survey (York County, Pennsylvania), 17522
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Charles Brown Papers, 1792/18882
- Charles Campbell Papers, 1743/18966
- Chester McNerney Collection, 1290/19501
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421
- Collection of Spanish Language Manuscripts, 1551/18581
- Colvin Papers, 1734/18392