- C. L. Worthington Papers, 1752/19381
- Cabell Family Papers, 1693/1913, bulk 1743/18237
- Campbell Family Papers, 1726/19203
- Carter Family Papers, 1667/1862, bulk 1792/186117
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Charles Campbell Papers, 1743/18964
- Chester McNerney Collection, 1290/19501
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421
- Collection of Spanish Language Manuscripts, 1551/18581
- Colvin Papers, 1734/18392
- Dunmore Family Papers (I) [in part photocopies], 1650/18995
- Earl Gregg Swem Genealogy Collection, 1719/19824
- Elizabeth River Parish Vestry Book, 1749/17612
- English Autographs and Signatures Collection, 1710/19151
- Ephemera Collection, 1800/20141