- Lexington Arsenal and Virginia Militia records, 1702/18393
- Manley Family papers, 1707/19533
- Maupin-Washington Papers, 1732/19323
- Overton family papers, 1727/1961, bulk 1781/18753
- Papers of the Preston and Related Radford Families, 1744-18953
- Richard Billups Papers, 1705/1857, bulk 1774/18223
- Richard G. Joynt Collection of British Manuscripts, 1593/20153
- Robert Hunt Land Papers, 1938/19423
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/19603
- Stearns Family Papers, 1714/19203
- Tyler Family Papers, Group A, 1716/19463
- Tyler Family Papers, Group G, 1645/19173
- University Archives Bound Volumes Collection, 1693/19933
- Upshur Family Papers, 1662/19363
- Washington and Lee University and Regional Virginia History Research Collection, 1609/20163