- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/19001
- Edwin W. Lynch Vietnam War protest collection, 1965/19756
- Eileen Peters, Compiler, Genealogy, 1887/199516
- Elizabeth Fairfax cookbook, 1694/17951
- Emory L. Kemp Papers regarding Industrial History, 1735/20212
- Ephemera Collection, 1800/20141
- Esther Holliday Green Collection (MS073), 1859/19821
- Fairfax Harrison Papers, 1736/19451
- Galt Papers (III), 1750/19911
- George Mason Papers, 1706/18581
- George Mason University Student Government records, 1968/20191
- Governor Arch A. Moore Jr. papers, 1950/19891
- Grigsby-Galt Papers, 1736/1982, bulk 1840/19301
- Hill Family Genealogy, 1700/1999, bulk 1980/199910
- Historic ephemera collection, 1796/19861