- A. E. Dick Howard papers, 1928/20171
- Austin-Twyman Papers, 1765/19391
- Blow Family Papers, 1613/1960, bulk 1770/18752
- Board of Visitors records, 1757/20231
- Cabell Family Papers, 1693/1913, bulk 1743/18231
- Campbell Family Papers, 1726/19201
- Carter Family Papers, 1667/1862, bulk 1792/18612
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Christian S. Hutter miscellany, 1602/19458
- Colvin Papers, 1734/18391
- Earl Gregg Swem Genealogy Collection, 1719/19821
- Edgar E. MacDonald papers, 1933/19931
- Edwin W. Lynch Vietnam War protest collection, 1965/19756
- Eileen Peters, Compiler, Genealogy, 1887/199514
- Elizabeth Fairfax cookbook, 1694/17951