- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Manuscripts Artifact Collection, 1800/20101
- Map Collection, 1629/19913
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19102
- Marshall W. Fishwick Collection, 1700/2007, bulk 1923/20072
- Mason C. Andrews Papers, 1777/2010, bulk 1950/19901
- McGavock Family Papers, 1760/188810
- Mercer County History, 1700/19351
- Methodist Files, 1784/20241
- Mills E. Godwin, Jr. Papers, 1712/1989, bulk 1947/19891
- Mining Industry, 1000/20001
- Morley Jeffers Williams Collection, 1602/19674
- Morris Family Papers
1727-19311
- Morton Genealogy Collection, 1830/19784