- Historic Maps of Europe, 1572/18451
- Jack Sandy Anderson, Compiler, Local History Articles and Genealogy Papers, 1600/2011, bulk 2000/20081
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19761
- Jerdone Family papers, 1753/18901
- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/19952
- Lexington Arsenal and Virginia Militia records, 1702/18391
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19101
- Morley Jeffers Williams Collection, 1602/19673
- Office of the President. James Blair Records, 1695/17472
- Peter family papers, 1722/19323
- Powell Family papers, 1775/19291
- Randolph H. Lytton historical Virginia collection3
- Richard Billups Papers, 1705/1857, bulk 1774/18222
- Robinson Family Papers, 1725/1940, bulk 1793/18481
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/19601