- George Mason Papers, 1706/18582
- George Washington collection, 1654/17992
- Historic Map and Government Documents Collection, 1630/19782
- J. Paul Hudson Papers, 1930/19982
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19762
- Jerdone Family papers, 1753/18902
- John Womack Wright Collection of Maps, 1675/19182
- Latin Exercise Book, 1672/17212
- Maben Jones Papers2
- Manley Family papers, 1707/19532
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19102
- Marshall W. Fishwick Collection, 1700/2007, bulk 1923/20072
- Richard Billups Papers, 1705/1857, bulk 1774/18222
- Robert Morton Hughes Papers, 1715/1940, bulk 1871/19332
- Robert S. Pace Collection
1669-19932