- Jim Comstock, Newspaper Editor and Collector, Papers, 1650/2003, bulk 1850/19951
- Lexington Arsenal and Virginia Militia records, 1702/18391
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19101
- Morley Jeffers Williams Collection, 1602/19673
- Office of the President. James Blair Records, 1695/17472
- Performing arts manuscripts collection, 1475/19842
- Peter family papers, 1722/19322
- Powell Family papers, 1775/19291
- Randolph H. Lytton Historical Virginia collection, 1670/20043
- Randolph H. Lytton historical Virginia collection3
- Richard Billups Papers, 1705/1857, bulk 1774/18221
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/19601
- Steve Wolfe, Collector, Historical Newspapers, 1666/19951
- The Independent Collection, 1680/19601
- Thomas G. and Louise Rowe Pullen Collection, 1655/17911