- Latin Exercise Book, 1672/17212
- Lee Nicholson Papers, 1827/19385
- Lexington Arsenal and Virginia Militia records, 1702/18393
- Lonnie L. Okes, Compiler, Akers, Lilly, and Ellison Families History, 1700/19611
- Lynch Family History, 1600/19401
- Maben Jones Papers2
- Malone Family Genealogy, 1700/19501
- Manley Family papers, 1707/19532
- Manuscript leaves from the Qur'an and Dala'il al-Khayrat, 1700/19001
- Manuscripts - People and Family Names, 1621/1949, bulk 18001
- Manuscripts Artifact Collection, 1800/20101
- Map Collection, 1629/19911
- Margaret Forbes Brand, Compiler, Genealogies, 1500/19651
- Margaret Grattan Weaver collection, 1707/1992, bulk 1857/19103
- Marshall W. Fishwick Collection, 1700/2007, bulk 1923/20072