- University Archives Artifact Collection, 1693/2014, bulk 1900/20113
- 17th and 18th century British periodicals, 1600/18002
- Armistead-Cocke Papers, 1680/19172
- Benefactions of Francis Nicholson, Esqr. to the Church & Clergy in North America, 1689/17042
- English Receipt and Home Remedy Manuscript Book, 1665/17042
- Hill Family Genealogy, 1700/1999, bulk 1980/19992
- Historic Map and Government Documents Collection, 1630/19782
- Historic manuscript collection, 1601/19332
- Historic map collection, 1675/19712
- J. Paul Hudson Papers, 1930/19982
- Jack Eric Morpurgo Papers, 1937/2000, bulk 1950/19702
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19762
- John Mason Diary, 1694/17022
- John Womack Wright Collection of Maps, 1675/19182
- King William III Letter to Sir Edmund Andros, 16942