- Hill Family Genealogy, 1700/1999, bulk 1980/19992
- James M. Guiher, Jr., Papers, 1835/2014, bulk 1927/19762
- Map Collection, 1629/19912
- Morley Jeffers Williams Collection, 1602/19672
- Sheet Music Collection, 1827/19742
- Tyler Family Papers, Group D, 1939/19512
- Virginia Counties Collection, 1600/2000, bulk 1730/18902
- Von Frieling's Salve collection, 1512/1977, bulk 1900/19322
- W. Jett Lauck papers, 1900/19522
- 17th and 18th century British periodicals, 1600/18001
- A. E. Dick Howard papers, 1928/20171
- Berkeley Family Papers
1536-present1
- Bevill Family Papers, 1558/1939, bulk 1558/17071
- Channing Moore Hall Papers, 1920/1953, bulk 1930/19531
- Collection of French Language Manuscripts, 1633/1942, bulk 1633/19421